Missouri Southern participates in the Advanced Placement Program sponsored by the College Entrance Examination Board. Credits are granted for course areas in which a student has completed Advanced Placement Examinations with a score of 3, 4, or 5. See the chart below for AP exams accepted by MSSU. To order AP scores, visit the College Board's Score Reporting Services page. MSSU's College Board code is 6322.
As credits not originally earned through instruction from MSSU, accepted credits will be applied as transfer credits on student transcript.
Transfer credits will be articulated for degree-seeking students. For non-degree seeking students, accepted credits may be articulated only if they are needed as pre-requisites for Missouri Southern courses.
| 2-D Art and Design | 3 | 3 | ART 101 |
| 3-D Art and Design | 3 | 3 | ART 103 |
| Art History | 3 | 3 | ART 110 |
| Biology | 3 | 4 | BIO 101 |
| Calculus AB | 3 | 5 | MATH 150 |
| Calculus BC | 3 | 10 | MATH 150 & MATH 250 |
| Chemistry | 3 | 5 | CHEM 151 |
| Computer Science A | 3 | 5 | CIS 110 |
| Drawing | 3 | 3 | ART 130 |
| Eng Language & Comp | 3 | 3 | ENG 101 |
| Eng Literature & Comp | 3 | 6 | ENG 101, ENG 250 |
| European History | 3 | 3 | HIST 130 OR HIST 140 |
| European History | 5 | 6 | HIST 130 & HIST 140 |
| Human Geography | 3 | 3 | GEOG 310 |
| Macroeconomics | 3 | 3 | ECON 201 |
| Microeconomics | 3 | 3 | ECON 202 |
| Music Theory | 3 | 3 | MUS Elective (ELEC 100) |
| Physics C: Electricity and Magnetism | 3 | 5 | PHYS 290 (4 cr. hrs.) PHYS 291 (1 cr. hr.) |
| Physics C: Mechanics | 3 | 4 | PHYS 270 |
| Psychology | 3 | 3 | PSY 100 |
| Spanish Language/Literature & Culture | 3 | 9 | SPAN 101, SPAN 102, SPAN 203 |
| Spanish Language/Literature & Culture | 4 | 12 | SPAN 101, SPAN 102, SPAN 203, SPAN 204 |
| Spanish Language/Literature & Culture | 5 | 15 | SPAN 101, SPAN 102, SPAN 203, SPAN 204, & SPAN 310 |
| Statistics | 3 | 3 | MATH 130 |
| United States Government & Politics | 3 | 3 | PSC 120 |
| United States History | 3 | 3 | HIST 110 OR HIST 120 |
| United States History | 5 | 6 | HIST 110 & HIST 120 |
| World History: Modern | 3 | 3 | HIST 180 |
